25 - 27 October, 2016
Novotel Berlin Am Tiergarten, Berlin, Germany

Dr. Richard Lewis

Global head, CADD
Novartis International AG, Switzerland

17:30 Building compound archives for future targets

  • Will the targets of the future be covered by the chemical matter of today?

  • Do we have the tools that can answer this question?

  • The interplay between druggability and ligandability

  • Future directions

Panel discussion will be followed by an Open Mic session: Join the discussion with the panel of experts and find collectively possible approaches and solutions

10:15 Analyzing building blocks diversity for DNA Encoded Library (DEL) design

  • DNA encoding: An opportunity to build massive hit-finding libraries

  • The challenge to cover chemical space appropriately

  • Current methods for selecting building blocks focus on 2D similarity and new Rooted 2D fingerprints

  • Development of complementary field-based descriptors and new clustering methods

  • Combination of tools with DEL technology to address the chemical space needed for hit finding against difficult future targets

Check out the incredible speaker line-up to see who will be joining Dr. Richard.

Download The Latest Agenda