25 - 27 October, 2016
Novotel Berlin Am Tiergarten, Berlin, Germany

Dr. Pawel Stanczak


Scientist
Dart Neuroscience, USA


10:00 Integrative methods to facilitate Fragment-Based Drug Discovery

  • Selection of biophysical methods for FBDD

  • Strengths and weaknesses of biophysical methods

  • Taking advantage of biophysical data to design the library of fragments


10:45 Workshop B - Prioritization of biophysical methods relative to the drug target and its mechanism of modulation

This interactive experience-based workshop will address the following approaches:

  • Prioritization of biophysical techniques to increase the success rate and speed up the FBDD process.

  • Discussion on PPI targets and prioritization of biophysical screenings for PPI targets. Selection of "intelligently designed" fragment libraries for those classes of targets.

  • Discussion on membrane proteins targets (mostly GPCRs) and prioritization of biophysical screenings for GPCRs.

  • Discussion on alternatives in FBDD (lack of crystal structures, low hit rate, etc.) using NMR spectroscopy and other biophysical tools.



Check out the incredible speaker line-up to see who will be joining Dr. Pawel.

Download The Latest Agenda