25 - 27 October, 2016
Novotel Berlin Am Tiergarten, Berlin, Germany

Dr. Jonathan S. Mason


Senior Research Fellow, Head of CADD
Heptares Therapeutics, UK


16:30 GPCRs: What do the diversity of new X-ray structures tell us about rational compound and library design?

  • Implications for design from the new binding sites discovered in recent GPCR X-ray structures

  • Using water in binding to generate new and modified property compounds

  • New structure-based approaches for the rational design of potency, selectivity and kinetics


17:30 Building compound archives for future targets

  • Will the targets of the future be covered by the chemical matter of today?

  • Do we have the tools that can answer this question?

  • The interplay between druggability and ligandability

  • Future directions

Panel discussion will be followed by an Open Mic session: Join the discussion with the panel of experts and find collectively possible approaches and solutions



Check out the incredible speaker line-up to see who will be joining Dr. Jonathan S..

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