Dr. Andrew PanniferHead of Medicinal Technologies
European Screening Centre, IMI European Lead Factory, UK
After a PhD in Molecular Biophysics at Oxford University, mapping the reaction mechanism of protein tyrosine phosphatases, I entered the pharmaceutical industry in 2002. Firstly at AZ and then at Pfizer, I performed structure-based drug design and crystallography and in 2010 joined the CRUK Beatson Institute Drug Discovery Programme to start up Structural Biology and Computational Chemistry. In 2013 I moved to the new European Lead Factory as the Head of Medicinal Technologies to start up cheminformatics and modelling and also to work with external IT solutions providers to build the ELF’s Honest Data Broker system for triaging HTS output.
Building the Joint European Compound Library
Early results from the screening campaigns
Exploiting the growing data set within the ELF database